Three people were wounded late on Wednesday when gunmen opened fire at locals in Assiut, Upper Egypt, state news agency MENA reported.
Unidentified assailants randomly shot at a café in the western part of the southern governorate of Assiut, leaving three people wounded before they fled the scene.
Police cordoned off the area and were searching for perpetrators.
Drive-by shootings and bombings targeting security forces have been commonplace amid an Islamist insurgency that has spiked since the army’s ouster of Islamist president Mohamed Morsi amid mass protests against his rule last summer.
Militants based in the Sinai Peninsula have killed hundreds of police and military personnel since then, with some Jihadist groups saying they are avenging a state crackdown that has killed hundreds of Islamists and jailed thousands of others.
The attacks have also led to civilian casualties.
Egyptian officials have voiced anxiety over militants infiltrating from neighbouring Libya, where a deadly militia rivalry has worsened over the past several months, and the rising threat from Islamic State, a militant Sunni group which has seized large swathes of Syria and Iraq.